Temperature, flow, pressure, fluid level, drainage, conductivity and pH may play a role in monitoring
the cleaning program.
The nature of the cleaning method will determine the critical parameters to
be monitored during cleaning. Critical operating parameter ranges should be established during cycle development and cleaning validation studies.
Instrumentation for monitoring critical parameters should be accurate and subject to a routine
calibration program.
Instrumentation may be placed directly in the process/cleaning stream or off-line for monitoring purposes. In-line instrumentation should be of appropriate sanitary design to prevent product or cleaning agent build-up and prevent "dead legs."
No comments:
Post a Comment