Cleaning Porous Equipment

The cleaning of porous equipment is a concern due to the ability of the surface to absorb drug.

In this case, dedication of the equipment would be the preferred choice. If the porous equipment or part cannot be dedicated, then cleaning procedures for soaking the material in a solvent or extracting absorbed drug may be required.

In these cases the sampling practices may need to be more stringent to ensure that absorbed drug and/or residual impurities are removed during the cleaning process.