Dedicated - Non-Dedicated Cleaning Equipment

1.The issues of dedicated and non-dedicated equipment can also arise when considering the
equipment used for cleaning.

2.CIP systems, for example, are frequently used for many different tanks in a single facility.

3.Inherently, the design of CIP systems should preclude cross-contamination through appropriate valving and back-flow prevention.

4..Care should be taken with shared devices which apply cleaning agents, such as spray balls or spray nozzles
which, themselves, may require cleaning.

5.Certainly any recirculation within the CIP system should be configured carefully during system design and monitored closely during routine
operation.

6.COP equipment, such as an ultrasonic sink, may also be used for multiple equipment loads.

7.With cleaning apparatus such as the sink, the removal of potential contaminants from the sink,
itself is a concern.

8. Sinks and washers frequently use recirculation systems to economically
remove residuals from surfaces without undue waste.

8.The cleanliness of the re-circulated materials should be evaluated during cleaning validation to ensure that contaminants are not
being re deposited on the equipment to be cleaned.